In May of 1607 three London Company ships landed at Jamestown Island in hopes and anticipation of finding riches. Things did not turn out quite like they planned. The island itself was a pear shape about 2 miles long and a mile wide. Surrounded by water and located some 60 miles inland from the ocean they felt it would be fairly defensible. Game, fish, and trees (for lumber) appeared to be in abundance. They would soon discover much of the island was marsh, in which swarms of enormous mosquitoes would breed. They found no fresh water springs and the shallow wells they dug would yield brackish salty water similar to the water that flowed right off shore in the James River. This lack of good drinking water contributed much sickness in the group. It did not take long for the local Indians (the Paspaheghs) to determine they did not care much for these strangers that were setting themselves up on Indian property. Despite all the enormous challenges faced this little foothold the British made in the Americas would continue on to become the first permanent English speaking location in the new world.
There is no formal city or town there today, but you can spend a good part of the day visiting the site of the original fort on the Island and then stopping by the Settlement. You can get there from Williamsburg by following Jamestown Road (Route 31), but the best drive is via the Colonial Parkway.
Jamestown Island is maintained by the National Park service and has a tremendous team of archeologist and interpreters that will help you understand the digs of the site of the original fort, early years of the settlement, and the artifacts that have been removed (over 1.5 million and counting).
The settlement about ½ mile away is the location of the recreated fort, replicas of the 3 ships, an Indian village, and some incredible galleries that will help you understand the British urge to come here, a little more about the natives that lived here during that time, and the final gallery that will give you detailed and in depth information about the Jamestown experiment.